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KLF5

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionDec 21, 2025
Entity authorityQ17853730 ↗
Source-derived summary

Krueppel-like factor 5 is a protein that in humans is encoded by the KLF5 gene.

Function

This gene encodes a member of the Kruppel-like factor subfamily of zinc finger proteins. Since the protein localizes to the nucleus and binds the epidermal growth factor response element, it is thought to be a transcription factor.

Interactions

KLF5 has been shown to interact with Protein SET.

Clinical significance

KLF5 expression has been linked to higher survival rates for lung cancer patients.

See also

Kruppel-like factors

References

Further reading

External links

KLF5+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Editorial summary

Begin with the source’s own compact description: “KLF5” is protein-coding gene in the species Homo sapiens. The dossier treats that line as a proposition to test through KLF5, protein-coding and gene, not as a finished interpretation.

Editorial reviewA practical orientation to terminology and classification, particularly when read beside dated observations, specimens or technical literature. The current 117-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. For this dossier, KLF5, protein-coding and gene is the immediate research focus.
Editorial analysis

Why this record matters

The phrase “protein-coding gene in the species Homo sapiens” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.

Evidence profile

Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Dec 21, 2025. The linked authority identifier is Q17853730. None of the 0 selected statements returned an explicit reference.

Critical limits

Scientific names, classifications and consensus can change while older terminology persists in catalogues and historical literature. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.

Best used for
  • Current terminology
  • Classification context
  • Finding cited technical literature
Verify next

Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.

Three-step research path

  1. Establish the record: confirm the title “KLF5”, its source revision and the description used here.
  2. Expand the search: follow KLF5 primary sources, KLF5 archive and KLF5 research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

  1. Which source most directly establishes the central claim about “KLF5”?
  2. Which observation, specimen, dataset or publication supports the account?
  3. Is the terminology current, historical or disputed?
Subject index

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Source & attribution

This entry incorporates text from “KLF5” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.