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Itai-itai disease

Japanese epidemic of cadmium poisoning

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionMay 19, 2026
Entity authorityQ183472
Source-derived summary

Itai-itai disease (Japanese: イタイイタイ病, Hepburn: itai-itai byō; lit. 'it hurts-it hurts disease') was the name given to the mass cadmium poisoning of Toyama Prefecture, Japan, starting around 1912. The term "itai-itai disease" was coined by locals for the severe pains (Japanese: 痛い itai) people with the condition felt in the spine and joints. Cadmium (Cd) poisoning can also cause softening of the bones and kidney failure. Effective treatments involve the use of chelators to promote urinary excretion of Cd. The cadmium was released into rivers by mining companies in the mountains, which were successfully sued for the damage. Remediation efforts in the affected region have been ongoing since 1972 and were mostly complete as of 2012. Monetary costs of the cleanup have been paid for in part by Japan's national government, Mitsui Mining, and the Gifu and Toyama prefectural governments. Itai-itai disease is known as one of the Four Big Pollution Diseases of Japan.

Etymology

The term itai-itai disease (in Japanese イタイイタイ病 itai-itai byō, "it hurts-it hurts disease" or "ouch-ouch disease") was coined by the affected locals for the severe pains that people with itai-itai disease felt in the spine and joints. In Japanese 痛い itai is used as an adjective meaning "painful" or as an interjection equivalent to "ouch".

Editorial summary

This brief starts where responsible research should: with the source description of “Itai-itai disease” as japanese epidemic of cadmium poisoning. Everything that follows is an evidence route, not borrowed authority.

Editorial reviewA concise reference frame for defining the subject, testing terminology and identifying the institution closest to the evidence. The current lead gives the account dated anchors—1912, 1972, 2012—that can be checked directly. The selected authority fields contribute no independent date. The account is most persuasive where Itai-itai, disease and Japanese can be independently traced.
Editorial analysis

Why this record matters

The subject matters to the general reference register because the source frames it as japanese epidemic of cadmium poisoning. Its deeper value depends on whether names, dates, institutions and citations support that framing.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated May 19, 2026. The linked authority identifier is Q183472. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1912, 1972 and 2012.

Critical limits

The absence of detail may reflect summary conventions rather than a lack of surviving documentation. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.

Best used for
  • Subject orientation
  • Search vocabulary
  • Locating named sources
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The closest primary source, responsible institution and strongest cited specialist reference.

Three-step research path

  1. Establish the record: confirm the title “Itai-itai disease”, its source revision and the description used here.
  2. Expand the search: follow Itai-itai disease primary sources, Itai-itai disease archive and Itai-itai research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

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Source & attribution

This entry incorporates text from Itai-itai disease” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.