Horizontal gene transfer
movement of genetic material between organisms other than by transmission from parent to offspring

Horizontal gene transfer (HGT) or lateral gene transfer (LGT) is the movement of genetic material between organisms other than by the ("vertical") transmission of DNA from parent to offspring (reproduction). HGT is an important factor in the evolution of many organisms. HGT is influencing scientific understanding of higher-order evolution while more significantly shifting perspectives on bacterial evolution.
Horizontal gene transfer is the primary mechanism for the spread of antibiotic resistance in bacteria, and plays an important role in the evolution of bacteria that can degrade novel compounds such as human-created pesticides and in the evolution, maintenance, and transmission of virulence. It often involves temperate bacteriophages and plasmids. Genes responsible for antibiotic resistance in one species of bacteria can be transferred to another species of bacteria through various mechanisms of HGT such as transformation, transduction and conjugation, subsequently arming the antibiotic resistant genes' recipient against antibiotics. The rapid spread of antibiotic resistance genes in this manner is becoming a challenge to manage in the field of medicine. Ecological factors may also play a role in the HGT of antibiotic resistant genes.
Horizontal gene transfer is recognized as a pervasive evolutionary process that distributes genes between divergent prokaryotic lineages and can also involve eukaryotes. HGT events are thought to occur less frequently in eukaryotes than in prokaryotes.
This brief starts where responsible research should: with the source description of “Horizontal gene transfer” as movement of genetic material between organisms other than by transmission from parent to offspring. Everything that follows is an evidence route, not borrowed authority.
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The subject matters to the history & society register because the source frames it as movement of genetic material between organisms other than by transmission from parent to offspring. Its deeper value depends on whether names, dates, institutions and citations support that framing.
Chronology, provenance and viewpoint should be read together before a broad social or political interpretation is accepted. The source revision retrieved here is dated Sep 17, 2026. The linked authority identifier is Q83185. The Library of Congress control number is sh85053873. None of the 1 selected statements returned an explicit reference.
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This entry incorporates text from “Horizontal gene transfer” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.