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5-HT2C receptor

Serotonin receptor protein distributed mainly in the choroid plexus

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 7, 2026
Entity authoritySource title only
Source-derived summary

The 5-HT2C receptor is a subtype of the 5-HT2 receptor that binds the endogenous neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Like all 5-HT2 receptors, it is a G protein-coupled receptor (GPCR) that is coupled to Gq/G11 and mediates excitatory neurotransmission. HTR2C denotes the human gene encoding for the receptor, that in humans is located on the X chromosome. As males have one copy of the gene and females have one of the two copies of the gene repressed, polymorphisms at this receptor can affect the two sexes to differing extent.

Editorial summary

Begin with the source’s own compact description: “5-HT2C receptor” is serotonin receptor protein distributed mainly in the choroid plexus. The dossier treats that line as a proposition to test through 5-HT2C, receptor and Serotonin, not as a finished interpretation.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current 88-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. For this dossier, 5-HT2C, receptor and Serotonin is the immediate research focus.
Editorial analysis

Why this record matters

The phrase “serotonin receptor protein distributed mainly in the choroid plexus” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.

Evidence profile

Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Sep 7, 2026.

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Source & attribution

This entry incorporates text from “5-HT2C receptor” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.