H1FOO
protein-coding gene in the species Homo sapiens
Histone H1oo is a protein that in humans is encoded by the H1FOO gene.
Function
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. The protein encoded is a member of the histone H1 family. This gene contains introns, unlike most histone genes. The protein encoded is a member of the histone H1 family. The related mouse gene is expressed only in oocytes.
It incorporates into sperm chromatin after fertilisation.
References
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
“H1FOO” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what H1FOO, protein-coding and gene can confirm, complicate or overturn.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jul 15, 2025. The linked authority identifier is Q18050364. None of the 0 selected statements returned an explicit reference.
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