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Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase

class of enzymes

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJul 6, 2025
Entity authorityQ5572338 ↗
Source-derived summary

The enzyme glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase (EC 3.1.4.51) catalyzes the reaction

6-(D-glucose-1-phospho)-D-mannosylglycoprotein + H2O

⇌

{\displaystyle \rightleftharpoons }

α-D-glucose 1-phosphate + D-mannosylglycoprotein

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is 6-(D-glucose-1-phospho)-D-mannosylglycoprotein glucose-1-phosphohydrolase. This enzyme is also called α-glucose-1-phosphate phosphodiesterase.

References

Srisomsap C, Richardson KL, Jay JC, Marchase RB (1989). "An α-glucose-1-phosphate phosphodiesterase is present in rat liver cytosol". J. Biol. Chem. 264 (34): 20540–6. doi:10.1016/S0021-9258(19)47096-8. PMID 2555363.

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The public source identifies “Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase” as class of enzymes. This brief keeps that definition visible, then builds a research path around Glucose-1-phospho-D-mannosylglycoprotein, phosphodiesterase and class.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current lead gives the account dated anchors—1989, 1016—that can be checked directly. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with Glucose-1-phospho-D-mannosylglycoprotein, phosphodiesterase and class providing the first useful test.
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This entry incorporates text from “Glucose-1-phospho-D-mannosylglycoprotein phosphodiesterase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.