Geotrichosis
opportunistic mycosis that has material basis in Galactomyces geotrichum, results in systemic infection in immunocompromised people
Geotrichosis is a mycosis caused by Geotrichum candidum.
Human colonization and disease
Geotrichum candidum is also a frequent member of the human microbiome, notably associated with skin, sputum and feces where it occurs in 25-30% of specimens. The fungus can cause an infection known as geotrichosis, affecting the oral, bronchial, skin and bronchopulmonary epithelia. The inoculum may arise from endogenous or exogenous sources.
In 1847 Bennett described Geotrichum candidum causing a superinfection in the tuberculous cavity. Bennett was able to differentiate infection by Geotrichum candidum from candidiasis, and diagnose the first case of geotrichosis. Other early medical case reports in 1916 and 1928 also described lung infections. Most cases affect the bronchopulmonary tree, although other sites can be involved, such as oral mucosa and vagina. Skin and gut infections are also known. Reported cases of geotrichosis have been characterized with symptoms of chronic or acute bronchitis.
This brief starts where responsible research should: with the source description of “Geotrichosis” as opportunistic mycosis that has material basis in Galactomyces geotrichum, results in systemic infection in immunocompromised people. Everything that follows is an evidence route, not borrowed authority.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Aug 8, 2023. The linked authority identifier is Q5548621. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1847, 1916 and 1928.
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This entry incorporates text from “Geotrichosis” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.