GPR171
protein-coding gene in the species Homo sapiens
G-protein coupled receptor 171 is a protein that in humans is encoded by the GPR171 gene. It has been recently deorphanised, with its endogenous agonist being a neuropeptide BigLEN which is a cleavage product of proSAAS. GPR174 has been found to be involved in processes such as pain, anxiety, and appetite regulation, as well as immune system function, and GPR174 agonists may represent a potential target for novel analgesic drugs. It seems to show sex-selective signalling, with effects seen in male mice often absent in female mice.
Begin with the source’s own compact description: “GPR171” is protein-coding gene in the species Homo sapiens. The dossier treats that line as a proposition to test through GPR171, protein-coding and gene, not as a finished interpretation.
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The phrase “protein-coding gene in the species Homo sapiens” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Aug 12, 2026. The linked authority identifier is Q18039689. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “GPR171” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.