Flavonolignan
class of chemical compounds, any lignan condensed with a 2-aryl-1-benzopyran skeleton and its substituted derivatives

Flavonolignans are natural phenols composed of a part flavonoid and a part phenylpropane.
Examples
Flavonolignans identified in Silybum marianum (milk thistle) silymarin complex include silibinin, silychristin, silydianin, dehydrosilybin, deoxysilycistin, deoxysilydianin, silandrin, silybinome, silyhermin and neosilyhermin and can be produced in vitro. Silibinin is found in the roots of S. marianum while silyamandin can be found in the fruit.
Hydnocarpin can be found naturally in Onopordon corymbosum and can be synthesised.
Scutellaprostin A, B, C, D, E and F can be isolated from Scutellaria prostrata and can also be synthesized.
Hydnowightin can be isolated from Hydnocarpus wightianus seeds.
Three flavonolignans derived from the flavone tricin have been isolated from the herb Avena sativa.
Palstatin has been isolated from the Amazon tree Hymeneae palustris.
Salcolin A and salcolin B can be found in Salsola collina.
Rhodiolin, the product of the oxidative coupling of coniferyl alcohol with the 7,8-dihydroxy grouping of the flavonol herbacetin, can be found in the rhizome of Rhodiola rosea.
The public source identifies “Flavonolignan” as class of chemical compounds, any lignan condensed with a 2-aryl-1-benzopyran skeleton and its substituted derivatives. This brief keeps that definition visible, then builds a research path around Flavonolignan, class and chemical.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jan 15, 2026. The linked authority identifier is Q3073502. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “Flavonolignan” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.