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Chemokine-like protein TAFA-4

protein-coding gene in the species Homo sapiens

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionJun 6, 2026
Entity authorityQ18052025 ↗
Source-derived summary

Chemokine-like protein TAFA-4 is a protein that in humans is encoded by the TAFA4 gene.

Function

This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Nov 2011].

References

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

Editorial summary

“Chemokine-like protein TAFA-4” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what Chemokine-like, protein and TAFA-4 can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current lead gives the account dated anchors—2011—that can be checked directly. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Chemokine-like, protein and TAFA-4.
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“Chemokine-like protein TAFA-4” is worth following because a concise public description often conceals a longer documentary argument. Here, Chemokine-like, protein and TAFA-4 provides the most credible route into that argument.

Evidence profile

Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Jun 6, 2026. The linked authority identifier is Q18052025. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2011.

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This entry incorporates text from “Chemokine-like protein TAFA-4” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.