Exercise-induced anaphylaxis
severe allergic reaction due to physical activity
Exercise-induced anaphylaxis (EIA, EIAn, EIAs) is a rare condition in which anaphylaxis, a serious or life-threatening allergic response, is brought on by physical activity. Approximately 5–15% of all reported cases of anaphylaxis are thought to be exercise-induced.
The exact proportion of the population with EIA is unknown, but a 2001 study of 76,229 Japanese junior high students showed that the frequency of EIA was 0.031%.
Exercise-induced anaphylaxis is not a widely known or understood condition, with the first research on the disorder only having been conducted in the past 40 years. A case report in 1979 on EIA was the first research of its kind, where a patient was described to experience anaphylactic shock related to exercise 5–24 hours following the consumption of shellfish.
The condition is thought to be more prevalent in women, with two studies of EIA patients reporting a ratio of 2:1 for females:males with the disorder. There is, however, thought to be no link to ethnicity.
Survey results from EIA patients have shown that the average number of attacks per year is 14.5. However, most sufferers of EIA report that both severity and frequency of attacks decrease over time.
Symptoms
The anaphylaxis campaign splits symptoms of EIA into two categories: mild and severe.
The public source identifies “Exercise-induced anaphylaxis” as severe allergic reaction due to physical activity. This brief keeps that definition visible, then builds a research path around Exercise-induced, anaphylaxis and severe.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Oct 9, 2025. The linked authority identifier is Q25399683. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2001 and 1979.
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This entry incorporates text from “Exercise-induced anaphylaxis” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.