Appendicitis
inflammation of the appendix
Appendicitis is inflammation of the appendix. Symptoms commonly include right lower abdominal pain, nausea, vomiting, fever and decreased appetite. However, approximately 40% of people do not have these typical symptoms. Severe complications of a ruptured appendix include widespread, painful inflammation of the inner lining of the abdominal wall and sepsis.
Appendicitis is primarily caused by a blockage of the hollow portion in the appendix. This blockage typically results from a faecolith, a calcified "stone" made of feces. Some studies show a correlation between appendicoliths and disease severity. Other factors such as inflamed lymphoid tissue from a viral infection, intestinal parasites, gallstone, or tumors may also lead to this blockage. When the appendix becomes blocked, it experiences increased pressure, reduced blood flow, and bacterial growth, resulting in inflammation. This combination of factors causes tissue injury and, ultimately, tissue death.
This brief starts where responsible research should: with the source description of “Appendicitis” as inflammation of the appendix. Everything that follows is an evidence route, not borrowed authority.
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Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Sep 18, 2026. The linked authority identifier is Q121041. The Library of Congress control number is sh85006090. 1 of 1 selected statements include explicit references; 1 carry qualifiers and 0 use preferred rank.
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This entry incorporates text from “Appendicitis” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.