Eileen Shore
American medical researcher
Eileen M. Shore is an American medical researcher and geneticist specializing in research of muscoskeletal disorders such as fibrodysplasia ossificans progressiva.
Education
Shore received her bachelor's degree in biology from the University of Notre Dame in 1976. She then earned a Master of Arts in biology at Indiana University in 1978. Subsequently, she received her PhD from the University of Pennsylvania in cell and molecular biology in 1987.
FOP research
Shore undertakes research into fibrodysplasia ossificans progressiva (FOP), a genetic disease that causes bone tissue to form outside the skeleton, known as heterotopic ossification.
In 1992, Shore and Frederick Kaplan initiated the FOP Research Laboratory.
Kaplan hired Shore because of her experience as a geneticist—she researched fruit fly larvae as a graduate student and studied mammalian embryology as a postdoctoral researcher.
In 2006, Shore and Kaplan published their findings on the genetic mutation that causes FOP as a paper entitled "A recurrent mutation in the BMP type I receptor ACVR1 causes inherited and sporadic fibrodysplasia ossificans progressiva". The cause of the disease was traced to a single mutation in the activin A receptor, type I gene.
Once the cause of the disease was identified, Shore became involved in efforts to control the disease and its symptoms.
“Eileen Shore” enters the record as american medical researcher. Crown Archives preserves that source wording while asking what Eileen, Shore and American can confirm, complicate or overturn.
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This entry incorporates text from “Eileen Shore” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.