Eyes absent homolog 1
protein-coding gene in the species Homo sapiens

Eyes absent homolog 1 is a protein that in humans is encoded by the EYA1 gene.
This gene encodes a member of the eyes absent (EYA) subfamily of proteins. The encoded protein may play a role in the developing kidney, branchial arches, eye, and ear. Mutations of this gene have been associated with branchiootorenal dysplasia syndrome, branchiootic syndrome, and sporadic cases of congenital cataracts and ocular anterior segment anomalies. A similar protein in mice can act as a transcriptional activator. Four transcript variants encoding three distinct isoforms have been identified for this gene.
Interactions
EYA1 has been shown to interact with SIX1.
“Eyes absent homolog 1” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what Eyes, absent and homolog can confirm, complicate or overturn.
Why this record matters
“Eyes absent homolog 1” is worth following because a concise public description often conceals a longer documentary argument. Here, Eyes, absent and homolog provides the most credible route into that argument.
Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Sep 22, 2026. The linked authority identifier is Q17917742. None of the 0 selected statements returned an explicit reference.
A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Check terminology, classification and the date of the cited evidence. Scientific names and technical consensus can change while older records retain historical value.
- Current terminology
- Classification context
- Finding cited technical literature
Primary datasets, specimen catalogues, standards bodies and the most recent peer-reviewed literature.
Three-step research path
- Establish the record: confirm the title “Eyes absent homolog 1”, its source revision and the description used here.
- Expand the search: follow Eyes absent homolog 1 primary sources, Eyes absent homolog 1 archive and Eyes research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “Eyes absent homolog 1”?
- Is the terminology current, historical or disputed?
- Has classification or technical consensus changed since the cited source?
Search terms from this dossier
This entry incorporates text from “Eyes absent homolog 1” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.