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Chondroitin-glucuronate 5-epimerase

class of enzymes

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionMar 10, 2025
Entity authorityQ5104527 ↗
Source-derived summary

In enzymology, a chondroitin-glucuronate 5-epimerase (EC 5.1.3.19) is an enzyme that catalyzes the chemical reaction

chondroitin D-glucuronate

⇌

{\displaystyle \rightleftharpoons }

dermatan L-iduronate

Hence, this enzyme has one substrate, chondroitin D-glucuronate, and one product, dermatan L-iduronate.

This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. The systematic name of this enzyme class is chondroitin-D-glucuronate 5-epimerase. Other names in common use include polyglucuronate 5-epimerase, dermatan-sulfate 5-epimerase, urunosyl C-5 epimerase, and chondroitin D-glucuronosyl 5-epimerase. This enzyme participates in chondroitin sulfate biosynthesis.

References

Malmstrom A, Aberg L (1982). "Biosynthesis of dermatan sulphate. Assay and properties of the uronosyl C-5 epimerase". Biochem. J. 201 (3): 489–93.

Editorial summary

“Chondroitin-glucuronate 5-epimerase” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what Chondroitin-glucuronate, 5-epimerase and class can confirm, complicate or overturn.

Editorial reviewA practical starting point whose main value is the path it opens into stronger specialist and primary sources. The current lead gives the account dated anchors—1982—that can be checked directly. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Chondroitin-glucuronate, 5-epimerase and class.
Editorial analysis

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“Chondroitin-glucuronate 5-epimerase” is worth following because a concise public description often conceals a longer documentary argument. Here, Chondroitin-glucuronate, 5-epimerase and class provides the most credible route into that argument.

Evidence profile

Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Mar 10, 2025. The linked authority identifier is Q5104527. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1982.

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Source & attribution

This entry incorporates text from “Chondroitin-glucuronate 5-epimerase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.