Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)
class of enzymes
Pyridoxal 5′-phosphate synthase (glutamine hydrolysing) (EC 4.3.3.6, PdxST) is an enzyme with systematic name D-ribose 5-phosphate,D-glyceraldehyde 3-phosphate pyridoxal 5′-phosphate-lyase. This enzyme catalyses the following chemical reaction
D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine
⇌
{\displaystyle \rightleftharpoons }
pyridoxal 5′-phosphate + L-glutamate + 3 H2O + phosphate (overall reaction)
(1a) L-glutamine + H2O
⇌
{\displaystyle \rightleftharpoons }
L-glutamate + NH3
(1b) D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + NH3
⇌
{\displaystyle \rightleftharpoons }
pyridoxal 5′-phosphate + 4 H2O + phosphate
The enzyme can also use ribulose 5-phosphate and dihydroxyacetone phosphate.
“Pyridoxal 5'-phosphate synthase (glutamine hydrolyzing)” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what Pyridoxal, 5'-phosphate and synthase can confirm, complicate or overturn.
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