Tyrosine-ester sulfotransferase
class of enzymes
Tyrosine-ester sulfotransferase (EC 2.8.2.9) is an enzyme that catalyzes the chemical reaction
The reaction converts methyl L-tyrosine methyl ester to L-tyrosine methyl ester 4-sulfate by transferring a sulfate group from the cofactor 3'-phosphoadenosine-5'-phosphosulfate (PAPS) and giving adenosine 3',5'-bisphosphate as a byproduct. The enzyme was characterised from rat liver.
This enzyme is a transferase, specifically a sulfotransferase, which transfer sulfur-containing groups. The systematic name of this enzyme class is 3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase. Other names in common use include aryl sulfotransferase IV, and L-tyrosine methyl ester sulfotransferase.
The public source identifies “Tyrosine-ester sulfotransferase” as class of enzymes. This brief keeps that definition visible, then builds a research path around Tyrosine-ester, sulfotransferase and class.
Why this record matters
A short description can identify a subject without explaining its stakes. For “Tyrosine-ester sulfotransferase”, the useful work is to connect “class of enzymes” to the records capable of establishing context and consequence.
Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Jul 30, 2026. The linked authority identifier is Q7861681. None of the 0 selected statements returned an explicit reference.
A concise general-reference account can conceal disagreements about scope, terminology or the weight assigned to individual sources. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
How to read it
Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.
- Subject orientation
- Search vocabulary
- Locating named sources
The closest primary source, responsible institution and strongest cited specialist reference.
Three-step research path
- Establish the record: confirm the title “Tyrosine-ester sulfotransferase”, its source revision and the description used here.
- Expand the search: follow Tyrosine-ester sulfotransferase primary sources, Tyrosine-ester sulfotransferase archive and Tyrosine-ester research across catalogues and specialist indexes.
- Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.
Questions for further research
- Which source most directly establishes the central claim about “Tyrosine-ester sulfotransferase”?
- What terminology or title could unlock a more precise catalogue search?
- Which institution is responsible for the underlying evidence?
Search terms from this dossier
This entry incorporates text from “Tyrosine-ester sulfotransferase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.