Nucleotide diphosphokinase
class of enzymes
In enzymology, a nucleotide diphosphokinase (EC 2.7.6.4) is an enzyme that catalyzes the chemical reaction
ATP + nucleoside 5'-phosphate
⇌
{\displaystyle \rightleftharpoons }
AMP + 5'-phosphonucleoside 3'-diphosphate
Thus, the two substrates of this enzyme are ATP and nucleoside 5'-phosphate, whereas its two products are AMP and 5'-phosphonucleoside 3'-diphosphate.
This enzyme belongs to the family of transferases, specifically those transferring two phosphorus-containing groups (diphosphotransferases). The systematic name of this enzyme class is ATP:nucleoside-5'-phosphate diphosphotransferase. Other names in common use include nucleotide pyrophosphokinase, ATP:nucleotide pyrophosphotransferase, ATP nucleotide 3'-pyrophosphokinase, and nucleotide 3'-pyrophosphokinase.
References
Murao S, Nishino T (1974). "Isolation and identification of ATP:nucleotide pyrophosphotransferase-producing microorganism". Agric. Biol. Chem. 38 (12): 2483–2489.
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