2,5-diaminovalerate transaminase
class of enzymes
In enzymology, a 2,5-diaminovalerate transaminase (EC 2.6.1.8) was a putative enzyme that would have catalyzed the chemical reaction
2,5-diaminopentanoate + 2-oxoglutarate
⇌
{\displaystyle \rightleftharpoons }
5-amino-2-oxopentanoate + L-glutamate
Thus, the two substrates of this enzyme would have been 2,5-diaminopentanoate and 2-oxoglutarate, whereas its two products would have been 5-amino-2-oxopentanoate and L-glutamate. The reaction however most likely does not happen.
It was thought to use one cofactor, pyridoxal phosphate.
Nomenclature
The enzyme would have belonged to the family of transferases, specifically the transaminases, which transfer nitrogenous groups. The systematic name of this enzyme class is 2,5-diaminopentanoate:2-oxoglutarate aminotransferase. Other names in common use include diamino-acid transaminase, and diamino acid aminotransferase.
References
Further reading
Roberts E (February 1954). "Studies of transamination". Archives of Biochemistry and Biophysics. 48 (2): 395–401.
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