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Methylglyoxal reductase (NADPH-dependent)

enzyme class

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionDec 12, 2025
Entity authorityQ2679993 ↗
Source-derived summary

In enzymology, methylglyoxal reductase (NADPH-dependent) (EC 1.1.1.283) is an enzyme that catalyzes the chemical reaction

The two substrates of this enzyme are (S)-lactaldehyde and oxidised nicotinamide adenine dinucleotide phosphate (NADP+). Its products are methylglyoxal, reduced NADPH, and a proton.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is lactaldehyde:NADP+ oxidoreductase. Other names in common use include lactaldehyde dehydrogenase (NADP+), and Gre2.

Editorial summary

Begin with the source’s own compact description: “Methylglyoxal reductase (NADPH-dependent)” is enzyme class. The dossier treats that line as a proposition to test through Methylglyoxal, reductase and NADPH-dependent, not as a finished interpretation.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current 83-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. For this dossier, Methylglyoxal, reductase and NADPH-dependent is the immediate research focus.
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Why this record matters

The phrase “enzyme class” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.

Evidence profile

The citation trail is more important than the brevity of the summary: it shows where individual claims can be examined in context. The source revision retrieved here is dated Dec 12, 2025. The linked authority identifier is Q2679993. None of the 0 selected statements returned an explicit reference.

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Source & attribution

This entry incorporates text from “Methylglyoxal reductase (NADPH-dependent)” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.