3(or 17)a-hydroxysteroid dehydrogenase
class of enzymes
3(or 17)alpha-hydroxysteroid dehydrogenase (EC 1.1.1.209, 3(17)alpha-hydroxysteroid dehydrogenase) is an enzyme with systematic name 3(or 17)alpha-hydroxysteroid:NAD(P)+ oxidoreductase. This enzyme catalyses the chemical reaction
androsterone + NAD(P)+
⇌
{\displaystyle \rightleftharpoons }
5alpha-androstane-3,17-dione + NAD(P)H + H+
This enzyme acts on the 3alpha-hydroxy group of androgens of the 5alpha-androstane series; and also, more slowly, on the 17alpha-hydroxy group of both androgenic and estrogenic substrates (cf. EC 1.1.1.51 3(or 17)beta-hydroxysteroid dehydrogenase).
“3(or 17)a-hydroxysteroid dehydrogenase” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what a-hydroxysteroid, dehydrogenase and class can confirm, complicate or overturn.
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Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Sep 22, 2024. The linked authority identifier is Q2646206. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “3(or 17)a-hydroxysteroid dehydrogenase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.