Haplogroup E-M123
human Y-chromosome haplogroup
In human genetics, Y Haplogroup E-M123 is a Y-chromosome haplogroup, and defined by the single nucleotide polymorphism (SNP) mutation M123. Like its closest relatives within the larger E-M215 haplogroup, E-M123 is found in Asia, Europe and Africa.
Origin
The Levant and East Africa have both been proposed as the most likely origin for this lineage rather than North Africa. On the African continent, E-M34 seems to be localized to Semitic speakers in Ethiopia, and it has not been detected in other populations in the region such as in Somalia, Kenya, Morocco, Algeria, Egypt.
Distribution
E-M123 is best known for its major sub-clade E-M34, which dominates this clade. However, earlier studies did not test for E-M34. Looking beyond its geographical patterns, E-M123 is also quite common in many Semitic language communities, including among Ashkenazi, and Sephardic Jews, accounting for over 10% of all male lines (Semino et al. 2004).
Subclade distribution
E-M123* (tested and definitely without E-M34)
Such cases are relatively rare, but the following have been reported.
Cruciani et al.
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