Dictyate
Prolonged resting phase in oogenesis
The dictyate or dictyotene is a prolonged resting phase in oogenesis. It occurs in the stage of meiotic prophase I in ootidogenesis. It starts late in fetal life and is terminated shortly before ovulation by the LH surge. Thus, although the majority of oocytes are produced in female fetuses before birth, these pre-eggs remain arrested in the dictyate stage until puberty commences and the cells complete ootidogenesis.
In both mouse and human, oocyte DNA of older individuals has substantially more double-strand breaks than that of younger individuals.
The dictyate appears to be an adaptation for efficiently removing damages in germ line DNA by homologous recombinational repair. Prophase arrested oocytes have a high capability for efficient repair of DNA damages. DNA repair capability appears to be a key quality control mechanism in the female germ line and a critical determinant of fertility.
Translation halt
There are a lot of mRNAs that have been transcribed but not translated during dictyate. Shortly before ovulation, the oocyte of interest activates these mRNA strains.
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This entry incorporates text from “Dictyate” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.