4-PhPr-2,5-DMA
pharmaceutical compound
4-(3-Phenylpropyl)-2,5-dimethoxyamphetamine (DOPP or DOPhPr), also known as 4-PhPr-2,5-DMA, is a serotonin receptor modulator of the phenethylamine, amphetamine, and DOx families. The properties and effects of 4-PhPr-2,5-DMA in humans do not appear to be known. It shows high affinity for both the serotonin 5-HT2A and 5-HT2C receptors and acts as a weak partial agonist or antagonist of the serotonin 5-HT2A receptor. The drug has lower affinity for the serotonin 5-HT2A receptor than its closely related positional isomer 4-PhPr-3,5-DMA. This is an apparent reversal of the usual situation with DOx and related drugs, in which the 2,5-dimethoxy pattern is optimal for serotonin 5-HT2A receptor interactions. 4-PhPhr-2,5-DMA was first described in the scientific literature by Richard Glennon and colleagues by 1989.
The public source identifies “4-PhPr-2,5-DMA” as pharmaceutical compound. This brief keeps that definition visible, then builds a research path around 4-PhPr-2, 5-DMA and pharmaceutical.
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This entry incorporates text from “4-PhPr-2,5-DMA” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.