2,5-Dimethoxy-4-chloroamphetamine
chemical compound
2,5-Dimethoxy-4-chloroamphetamine (DOC) is a psychedelic drug of the phenethylamine, amphetamine, and DOx families. It is taken orally.
The drug acts as a serotonin 5-HT2 receptor agonist, including of the serotonin 5-HT2A receptor. Analogues of DOC include 2C-C, DOB, DOI, DOM, among others.
DOC was first described in the scientific literature by Ronald Coutts and Jerry Malicky in 1973. Subsequently, it was described in greater detail by Alexander Shulgin in his 1991 book PiHKAL (Phenethylamines I Have Known and Loved). Recreational availability and use of DOC are rare. The drug is expected to become a controlled substance in the United States in the near future as of 2025.
Use and effects
In his book PiHKAL (Phenethylamines I Have Known and Loved), Alexander Shulgin lists DOC's dose as 1.5 to 3 mg orally and its duration as 12 to 24 hours. The effects of DOC have been reported to include closed-eye imagery, visuals, introspection, lightheadedness, disconnectedness, and spaciness, among others.
“2,5-Dimethoxy-4-chloroamphetamine” enters the record as chemical compound. Crown Archives preserves that source wording while asking what 5-Dimethoxy-4-chloroamphetamine, chemical and compound can confirm, complicate or overturn.
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This entry incorporates text from “2,5-Dimethoxy-4-chloroamphetamine” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.