Dynein axonemal light chain 1
protein-coding gene in the species Homo sapiens

Dynein axonemal light chain 1, (LC1) is a protein that in humans is encoded by the DNAL1 gene.
Function
LC1 is a component of outer dynein arms, which contain the molecular motors for ATP-dependent cilia movement.
Clinical significance
Mutations in the DNAL1 gene are associated with primary ciliary dyskinesia.
References
External links
GeneReviews/NCBI/NIH/UW entry on Primary Ciliary Dyskinesia
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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