DCP1A
protein-coding gene in the species Homo sapiens
mRNA-decapping enzyme 1A is a protein that in humans is encoded by the DCP1A gene.
Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway.
Interactions
DCP1A has been shown to interact with DCP2 and UPF1. It has also been shown to colocalize with GW182, and other markers of P-body. Human DCP1A is heterotrimeric, and makes contacts with the scaffold EDC3/4. The Arabidopsis thaliana homolog interacts with the plant specific type XI myosin motor protein.
“DCP1A” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what DCP1A, protein-coding and gene can confirm, complicate or overturn.
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The date and method of observation matter as much as the stated conclusion, especially where classification or consensus has changed. The source revision retrieved here is dated Jul 16, 2025. The linked authority identifier is Q18042066. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “DCP1A” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.