Glyceraldehyde-3-phosphate dehydrogenase (NADP+)
class of enzymes
Glyceraldehyde-3-phosphate dehydrogenase (NADP+) (EC 1.2.1.9) (GAPN) is an enzyme that irreversibly catalyzes the oxidation of glyceraldehyde-3-phosphate (GAP) to 3-phosphoglycerate (3-PG or 3-PGA) using the reduction of NADP+ to NADPH. GAPN is used in a variant of glycolysis that conserves energy as NADPH rather than as ATP. The NADPH and 3-PG can then be used for synthesis. The most familiar variant of glycolysis uses glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and phosphoglycerate kinase to produce ATP. GAPDH is phosphorylating. GAPN is non-phosphorylating.
GAPN was reported first by Rosenberg and Arnon in 1954. It has been found in plants, algae, and bacteria.
“Glyceraldehyde-3-phosphate dehydrogenase (NADP+)” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what Glyceraldehyde-3-phosphate, dehydrogenase and NADP can confirm, complicate or overturn.
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This entry incorporates text from “Glyceraldehyde-3-phosphate dehydrogenase (NADP+)” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.