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David Cushman

American biochemist (1939-2000)

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Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 6, 2026
Entity authorityQ5232740 ↗
Source-derived summary

David Cushman (November 15, 1939 – August 14, 2000) was an American biochemist who co-invented captopril, the first of the (angiotensin-converting enzyme) ACE inhibitors used in the treatment of cardiovascular disease. With Miguel A. Ondetti, Dr. Cushman won the 1999 Lasker Award for: "developing an innovative approach to drug design based on protein structure and using it to create the ACE inhibitors, powerful oral agents for the treatment of high blood pressure, heart failure, and diabetic kidney disease."

Biography

David Cushman was born in Indianapolis, Indiana. He was the son of Wayne B. and Mildred M. and married to Linda L. Kranch. They have two children together named Michael and Laura Cushman. In high school, Dr. Cushman didn't have a drive or reason to succeed academically until he found a class he enjoyed because of the teacher. He went on to Wabash College in Crawfordsville, Indiana where he majored in Zoology and minored in Chemistry. His tenacious attitude gave him the boost to get magna cum laude. He was a first-generation college student in his family and grew up poor.

Editorial summary

The public source identifies “David Cushman” as american biochemist (1939-2000). This brief keeps that definition visible, then builds a research path around David, Cushman and American.

Editorial reviewA practical starting point whose main value is the path it opens into stronger specialist and primary sources. The current lead gives the account dated anchors—1939, 2000, 1999—that can be checked directly. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with David, Cushman and American providing the first useful test.
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A short description can identify a subject without explaining its stakes. For “David Cushman”, the useful work is to connect “american biochemist (1939-2000)” to the records capable of establishing context and consequence.

Evidence profile

The citation trail is more important than the brevity of the summary: it shows where individual claims can be examined in context. The source revision retrieved here is dated Sep 6, 2026. The linked authority identifier is Q5232740. The first chronological checks are 1939, 2000 and 1999.

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Source & attribution

This entry incorporates text from “David Cushman” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.