Chymotrypsinogen B2
protein-coding gene in the species Homo sapiens
Chymotrypsinogen B2 is a protein that in humans is encoded by the CTRB2 gene. Chymotrypsinogen B2 is an inactive precursor enzyme (or zymogen) for an active enzyme, which is sometimes called chymotrypsin B2. This enzyme is an isozyme of chymotrypsin that participates in the digestion and breakdown of proteins. The inactive protein is produced by the acinar cells in the pancreas, then secreted into the small intestines where it is cleaved and activated by trypsin, another digestive enzyme. After cleaving, Chymotrypsin B2 is composed of 3 peptide chains which remain connected via disulfide bridges.
Begin with the source’s own compact description: “Chymotrypsinogen B2” is protein-coding gene in the species Homo sapiens. The dossier treats that line as a proposition to test through Chymotrypsinogen, protein-coding and gene, not as a finished interpretation.
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This entry incorporates text from “Chymotrypsinogen B2” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.