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Bile-acid 7alpha-dehydroxylase

class of enzymes

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionAug 18, 2025
Entity authorityQ4170138 ↗
Source-derived summary

Bile-acid 7alpha-dehydroxylase (EC 1.17.99.5, cholate 7alpha-dehydroxylase, 7alpha-dehydroxylase, bile acid 7-dehydroxylase) was thought to be an enzyme with systematic name deoxycholate:NAD+ oxidoreductase.

However, it was later shown that the dehydroxylation is carried out by seven different enzymes, catalyzing a total of 8 reactions. The enzymes are EC 6.2.1.7, EC 1.1.1.395, EC 1.3.1.115, EC 2.8.3.25, EC 4.2.1.106, EC 1.3.1.114, and EC 1.1.1.52.

Editorial summary

This brief starts where responsible research should: with the source description of “Bile-acid 7alpha-dehydroxylase” as class of enzymes. Everything that follows is an evidence route, not borrowed authority.

Editorial reviewA dependable orientation record for establishing vocabulary, names and a first evidence trail. The current 60-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. The account is most persuasive where Bile-acid, 7alpha-dehydroxylase and class can be independently traced.
Editorial analysis

Why this record matters

The subject matters to the general reference register because the source frames it as class of enzymes. Its deeper value depends on whether names, dates, institutions and citations support that framing.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Aug 18, 2025. The linked authority identifier is Q4170138.

Critical limits

Overview language is designed for orientation and should not be treated as a substitute for the evidence cited beneath it. The source lead contains qualifying language; that uncertainty should survive quotation, summary and reuse. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

How to read it

Use the entry as an orientation point, then follow its citations and revision history. Names, dates and institutional relationships should be checked against the original record.

Best used for
  • Subject orientation
  • Search vocabulary
  • Locating named sources
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The closest primary source, responsible institution and strongest cited specialist reference.

Three-step research path

  1. Establish the record: confirm the title “Bile-acid 7alpha-dehydroxylase”, its source revision and the description used here.
  2. Expand the search: follow Bile-acid 7alpha-dehydroxylase primary sources, Bile-acid 7alpha-dehydroxylase archive and Bile-acid research across catalogues and specialist indexes.
  3. Test the account: compare the strongest cited source with the responsible institution’s current record and note any disagreement.

Questions for further research

  1. Which source most directly establishes the central claim about “Bile-acid 7alpha-dehydroxylase”?
  2. Which institution is responsible for the underlying evidence?
  3. Which cited source is closest to the event, object or claim?
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Source & attribution

This entry incorporates text from “Bile-acid 7alpha-dehydroxylase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.