Promazine
chemical compound
Promazine (brand name Sparine among others), is used as a short-term add-on treatment for psychomotor agitation. Its approved uses in people is limited, but is used as a tranquilizer in veterinary medicine. It has weak antipsychotic effects but is generally not used to treat psychosis.
It acts similar to chlorpromazine and causes sedation. It has predominantly anticholinergic side effects, though extrapyramidal side effects are not uncommon. It belongs to the typical antipsychotic and phenothiazine class of drugs.
Promazine was approved for medical use in the United States in the 1950s, although it is no longer commercially available there.
Uses
Promazine is a short-term add-on treatment for psychomotor agitation.
Adverse effects
Common side effects include agitation, amenorrhea, arrhythmias, constipation, drowsiness and dizziness, dry mouth, impotence, tiredness, galactorrhoea, gynecomastia, hyperglycemia, insomnia, hypotension, prolonged QT, seizures, tremor, vomiting and weight gain, among others.
Overdose
In overdose, it may cause hypotension, hypothermia, tachycardia, and arrhythmia.
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