Carmela Abraham
American neuroscientist

Carmela R. Abraham is an American neuroscientist who focuses on the study of Alzheimer's disease.
Early life and education
Abraham earned her Bachelor of Science degree in Biology from Tel Aviv University and her PhD in Neuroscience from Harvard University. In 1990, Abraham was the recipient of The Neuroscience Education and Research Foundation Award for an Outstanding Promise as a Young Alzheimer Investigator. She was also the first Rappaport Scholar at the Center for Neurologic Diseases at Brigham and Women's Hospital, and the recipient of the Zenith and Temple awards from the Alzheimer's Association.
Career
Upon completing her PhD, Abraham accepted a position at Boston University School of Medicine (BU) as a Professor of Biochemistry and Pharmacology & Experimental Therapeutics. In this role, she was the recipient of a $200,000 grant from the Alzheimer's Association to support her research on drug therapy for Alzheimer's disease. Later, she identified Klotho, an anti-aging and anti-cancer protein that could reduce ageing in the brain. Her research team conducted a high throughput screen of 150,000 molecules, which led to the identification of three lead compounds that could prevent age-related diseases and overall healthier ageing. Following this, Abraham and her research team identified the importance of Klotho on the health of myelin and found small molecules that could form the basis for the development of therapeutic drugs.
During her time at BU, Abraham also co-founded Klogene Therapeutics, a pre-clinical stage gene therapy startup company developing novel treatments for neurodegenerative diseases.
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