Byzantine–Sasanian War of 602–628
the last war between Byzantine Empire and Persia

The Byzantine–Sasanian War of 602–628, also called the Last Great War of Antiquity, was fought between the Byzantine Empire and the Sasanian Empire. It was the final and most devastating conflict of the Roman–Persian wars (54 BC – AD 628). The previous war between the two powers had ended in 591 after the emperor Maurice helped the Sasanian king Khosrow II regain his throne. In 602, Maurice was murdered by his political rival Phocas. Khosrow declared war, ostensibly to avenge the death of the deposed emperor Maurice. This became a decades-long conflict, the longest war in the series, and was fought throughout the Middle East, the Aegean Sea, and before the walls of Constantinople itself.
From 602 to 622, the Sassanians gradually conquered much of the Levant, parts of Anatolia, and—for the first time—Egypt and several islands in the Aegean Sea. The counter-attacks of the new Byzantine emperor Heraclius from 622 to 626 eventually forced the Persians onto the defensive. Allied with the Avars and Slavs, the Persians attempted to take Constantinople in 626, but were defeated. In 627, allied with Turks, Heraclius invaded the heartland of Persia.
The public source identifies “Byzantine–Sasanian War of 602–628” as the last war between Byzantine Empire and Persia. This brief keeps that definition visible, then builds a research path around Byzantine, Sasanian and last.
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Chronology, provenance and viewpoint should be read together before a broad social or political interpretation is accepted. The source revision retrieved here is dated Sep 20, 2026. The linked authority identifier is Q2326099. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “Byzantine–Sasanian War of 602–628” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.