Adenosylcobinamide-phosphate synthase
class of enzymes
Adenosylcobinamide-phosphate synthase (EC 6.3.1.10, CbiB) is an enzyme with systematic name adenosylcobyric acid:(R)-1-aminopropan-2-yl phosphate ligase (ADP-forming). This enzyme catalyses the following chemical reaction
(1) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-yl phosphate
⇌
{\displaystyle \rightleftharpoons }
ADP + phosphate + adenosylcobinamide phosphate
(2) ATP + adenosylcobyric acid + (R)-1-aminopropan-2-ol
⇌
{\displaystyle \rightleftharpoons }
ADP + phosphate + adenosylcobinamide
One of the substrates, (R)-1-aminopropan-2-yl phosphate, is produced by CobD (EC 4.1.1.81). This enzyme is part of the biosynthetic pathway to cobalamin (vitamin B12) in bacteria.
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This entry incorporates text from “Adenosylcobinamide-phosphate synthase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.