Mebeverine
chemical compound
Mebeverine is a drug used to alleviate some of the symptoms of irritable bowel syndrome. It works by relaxing the muscles in and around the gut.
Medical use
Mebeverine is used to alleviate some of the symptoms of irritable bowel syndrome (IBS) and related conditions; specifically stomach pain and cramps, persistent diarrhoea, and flatulence.
Historically data from controlled clinical trials have not found a difference from placebo or statistically significant results in the global improvement of IBS.
However, a 2022 systematic review found that Mebeverine is an effective treatment option in IBS, with a good safety profile and low frequency of adverse effects.
It has not been tested in pregnant women nor in pregnant animals so pregnant women should not take it; it is expressed at low levels in breast milk, while no adverse effects have been reported in infants, breastfeeding women should not take this drug.
Adverse effects
Adverse effects include hypersensitivity reactions and allergic reactions, immune system disorders, skin disorders including hives, oedema and widespread rashes.
Additionally, the following adverse effects have been reported: heartburn, indigestion, tiredness, diarrhoea, constipation, loss of appetite, general malaise, dizziness, insomnia, headache, and decreased pulse rate.
It does not have systemic anticholinergic side effects.
Mebeverine can, on highly rare occasions, cause drug-induced acute angle closure glaucoma.
In a urine drug-screening test, mebeverine can affect a false positive result for amphetamines.
This brief starts where responsible research should: with the source description of “Mebeverine” as chemical compound. Everything that follows is an evidence route, not borrowed authority.
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Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Aug 21, 2026. The linked authority identifier is Q418167. None of the 0 selected statements returned an explicit reference. The first chronological checks are 2022.
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This entry incorporates text from “Mebeverine” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.