Collagen, type IV, alpha 5
mammalian protein found in Homo sapiens
Collagen alpha-5(IV) chain is a protein that in humans is encoded by the COL4A5 gene.
This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Mutations in this gene are associated with X-linked Alport syndrome, also known as hereditary nephritis. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Three transcript variants have been identified for this gene.
“Collagen, type IV, alpha 5” enters the record as mammalian protein found in Homo sapiens. Crown Archives preserves that source wording while asking what Collagen, type and alpha can confirm, complicate or overturn.
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