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ANP32E

protein-coding gene in the species Homo sapiens

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Science and natureInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionSep 14, 2026
Entity authorityQ18047058 ↗
Source-derived summary

Acidic leucine-rich nuclear phosphoprotein 32 family member E is a protein that in humans is encoded by the ANP32E gene. The ANP32E gene is located on chromosome 1q22.

Function

In mammalian cells, ANP32E has been shown to be an H2A.Z chaperone capable of promoting the removal of H2A.Z from chromatin. In brain tissue, ANP32E together with Cpd1 regulate protein phosphatase 2A activity at synapses during synaptogenesis and has been observed to form a complex with ANP32A and SET that stabilizes short-lived mRNAs containing AU-rich elements, as well as having acetyltransferase inhibitory activity (in a complex with SET) and having a role in chromatin remodeling and transcriptional regulation.

See also

ANP32A, ANP32B, ANP32C, ANP32D

References

Further reading

External links

Human ANP32E genome location and ANP32E gene details page in the UCSC Genome Browser.

Editorial summary

“ANP32E” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what ANP32E, protein-coding and gene can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current 132-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its strongest next move is a source search built around ANP32E, protein-coding and gene.
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Why this record matters

“ANP32E” is worth following because a concise public description often conceals a longer documentary argument. Here, ANP32E, protein-coding and gene provides the most credible route into that argument.

Evidence profile

Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Sep 14, 2026. The linked authority identifier is Q18047058. None of the 0 selected statements returned an explicit reference.

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Source & attribution

This entry incorporates text from “ANP32E” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.