ADP-specific glucokinase
protein-coding gene in the species Homo sapiens
ADP-specific glucokinase (EC 2.7.1.147) also known as ADP-dependent glucokinase is an enzyme that catalyzes the chemical reaction
The enzyme characterised from Pyrococcus furiosus converts D-glucose to its monophosphate, glucose 6-phosphate, by transferring a phosphate group from the cofactor, adenosine diphosphate (ADP), which is converted to adenosine monophosphate (AMP). A similar enzyme has also been found in Thermococcus kodakarensis, where it acts on glucosamine as well as glucose.
In humans, the ADP-dependent glucokinase is encoded by the ADPGK gene.
Structural studies
Examples of the ADP-dependent glucokinase structure solved by x-ray crystallography include the enzyme from mouse PDB accession code 5CCF and Archaea PDB: 1GC5.
References
External links
Human ADPGK genome location and ADPGK gene details page in the UCSC Genome Browser.
“ADP-specific glucokinase” enters the record as protein-coding gene in the species Homo sapiens. Crown Archives preserves that source wording while asking what ADP-specific, glucokinase and protein-coding can confirm, complicate or overturn.
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