ABCB6
protein-coding gene in the species Homo sapiens
ATP-binding cassette super-family B member 6, mitochondrial is a protein that in humans is encoded by the ABCB6 gene.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This half-transporter likely plays a role in mitochondrial function. Localized to 2q26, this gene is considered a candidate gene for Dyschromatosis Universalis Hereditaria, a disorder of skin pigment metabolism. The protein also carries the Lan antigen, which defines the Lan blood group system.
See also
ATP-binding cassette transporter
References
Further reading
External links
ABCB6+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
ABCB6 human gene location in the UCSC Genome Browser.
Begin with the source’s own compact description: “ABCB6” is protein-coding gene in the species Homo sapiens. The dossier treats that line as a proposition to test through ABCB6, protein-coding and gene, not as a finished interpretation.
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The phrase “protein-coding gene in the species Homo sapiens” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Sep 13, 2026. The linked authority identifier is Q18034991. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “ABCB6” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.