Dimethandrolone undecanoate
chemical compound
Dimethandrolone undecanoate (DMAU), also known by its developmental code name CDB-4521, is an experimental androgen/anabolic steroid (AAS) and progestogen medication which is under development as a potential birth control pill for men. It is taken by mouth, but can also be given by injection into muscle.
Side effects of DMAU include mild weight gain and mild decreases in levels of HDL cholesterol. It may also cause low estrogen levels and associated symptoms such as reduced sexual function and decreased bone mineral density. DMAU is an AAS, and hence is an agonist of the androgen receptor, the biological target of androgens like testosterone. It is also a progestin, or a synthetic progestogen, and hence is an agonist of the progesterone receptor, the biological target of progestogens like progesterone. Due to its androgenic and progestogenic activity, DMAU has antigonadotropic effects. These effects result in reversible suppression of sperm production and are responsible for the contraceptive effects of DMAU in men. The medication has no estrogenic activity. DMAU is a prodrug of dimethandrolone.
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