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Methylenedioxycathinone

chemical compound

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Science and natureInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionMar 1, 2026
Entity authorityQ6823978 ↗
Source-derived summary

3,4-Methylenedioxycathinone (MDC, MDCATH), also known as β-keto-3,4-methylenedioxyamphetamine (β-keto-MDA or βk-MDA), is an entactogen and stimulant drug of the phenethylamine, amphetamine, and cathinone families related to methylone (βk-MDMA or MDMC). It is the β-keto analogue of MDA.

Like methylone, MDC is a serotonin–norepinephrine–dopamine releasing agent (SNDRA). In contrast to MDA and MDMA, MDC shows no activity at the serotonin 5-HT2 receptors, but does retain much weaker affinity for the rodent trace amine-associated receptor 1 (TAAR1).

The drug was patented as an antidepressant and antiparkinsonian agent by Peyton Jacob III and Alexander Shulgin in 1996. MDC and other non-N-substituted cathinones such as cathinone itself are chemically unstable due rapidly forming biologically inactive dimers and this has limited their prevalence.

Editorial summary

“Methylenedioxycathinone” enters the record as chemical compound. Crown Archives preserves that source wording while asking what Methylenedioxycathinone, chemical and compound can confirm, complicate or overturn.

Editorial reviewUseful for establishing the present vocabulary of the subject while preserving a route back to the evidence on which that vocabulary rests. The current lead gives the account dated anchors—1996—that can be checked directly. The selected authority fields contribute no independent date. Its strongest next move is a source search built around Methylenedioxycathinone, chemical and compound.
Editorial analysis

Why this record matters

“Methylenedioxycathinone” is worth following because a concise public description often conceals a longer documentary argument. Here, Methylenedioxycathinone, chemical and compound provides the most credible route into that argument.

Evidence profile

Stable identifiers, scientific names and standards terminology offer the best bridge between this overview and specialist evidence. The source revision retrieved here is dated Mar 1, 2026. The linked authority identifier is Q6823978. None of the 0 selected statements returned an explicit reference. The first chronological checks are 1996.

Critical limits

A general summary may omit uncertainty, sample limits or methodological disagreement that is explicit in the technical record. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.

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Source & attribution

This entry incorporates text from “Methylenedioxycathinone” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.