2C-AL
chemical compound

2C-AL, also known as 4-allyl-2,5-dimethoxyphenethylamine, is a drug from the substituted phenethylamine family which acts as an agonist of the 5-HT2A receptor, with an EC50Tooltip half-maximal effective concentration of 2.15 nM at 5-HT2A vs. 77.71 nM at 5-HT2B, and produces a head-twitch response in animal studies. It was first discussed as a hypothetical compound in Daniel Trachsel's 2013 review of the field after his successful synthesis of the related compounds 2C-V and 2C-YN, and finally synthesised by a team at Gilgamesh Pharmaceuticals in 2020 using a different synthetic route from that employed by Trachsel. It is a controlled substance in Canada under phenethylamine blanket-ban language.
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