YWHAG
protein-coding gene in the species Homo sapiens
14-3-3 protein gamma is a protein that in humans is encoded by the YWHAG gene.
This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.
Interactions
YWHAG has been shown to interact with C-Raf, EPB41L3, KIF1C and Stratifin.
Begin with the source’s own compact description: “YWHAG” is protein-coding gene in the species Homo sapiens. The dossier treats that line as a proposition to test through YWHAG, protein-coding and gene, not as a finished interpretation.
Why this record matters
The phrase “protein-coding gene in the species Homo sapiens” supplies a clear boundary for inquiry. It also exposes the unanswered questions: who defined that boundary, when it became stable and which sources sit outside it.
Datasets, specimens, observations and peer-reviewed methods provide the appropriate test for the technical claims summarized here. The source revision retrieved here is dated Feb 19, 2026. The linked authority identifier is Q18032408. None of the 0 selected statements returned an explicit reference.
Scientific names, classifications and consensus can change while older terminology persists in catalogues and historical literature. The lead is largely declarative, so disagreement and counter-evidence require a deliberate search beyond the opening account. Authority statements aid reconciliation but still require their own references, qualifiers and ranks to be checked.
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This entry incorporates text from “YWHAG” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.