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3-Isopropylmalate dehydrogenase

InterPro Family

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General referenceInterpretive dossier study · Crown Archives visual atlas
Record originEnglish Wikipedia
Text licenseCC BY-SA 4.0
Source revisionNov 27, 2025
Entity authorityQ24740415 ↗
Source-derived summary

3-Isopropylmalate dehydrogenase (EC 1.1.1.85) is an enzyme that is a part of the isopropylmalate dehydrogenase family, which catalyzes the overall chemical reaction:

The first step is an oxidation reaction in which the cofactor, oxidised nicotinamide adenine dinucleotide (NAD+), converts the hydroxy group of the malic acid derivative into the corresponding keto group. This spontaneously decarboxylates to give the observed product.

Editorial summary

The public source identifies “3-Isopropylmalate dehydrogenase” as interPro Family. This brief keeps that definition visible, then builds a research path around 3-Isopropylmalate, dehydrogenase and InterPro.

Editorial reviewA practical starting point whose main value is the path it opens into stronger specialist and primary sources. The current 60-word lead offers orientation but no explicit four-digit date, so chronology should not be assumed. The selected authority fields contribute no independent date. Its value is orientation rather than verdict, with 3-Isopropylmalate, dehydrogenase and InterPro providing the first useful test.
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A short description can identify a subject without explaining its stakes. For “3-Isopropylmalate dehydrogenase”, the useful work is to connect “interPro Family” to the records capable of establishing context and consequence.

Evidence profile

Named sources, stable identifiers and responsible institutions provide the strongest route from overview to verifiable evidence. The source revision retrieved here is dated Nov 27, 2025. The linked authority identifier is Q24740415. None of the 0 selected statements returned an explicit reference.

Critical limits

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  2. Expand the search: follow 3-Isopropylmalate dehydrogenase primary sources, 3-Isopropylmalate dehydrogenase archive and 3-Isopropylmalate research across catalogues and specialist indexes.
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Source & attribution

This entry incorporates text from “3-Isopropylmalate dehydrogenase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.