24-hydroxycholesterol 7alpha-hydroxylase
class of enzymes
In enzymology, a 24-hydroxycholesterol 7alpha-hydroxylase (EC 1.14.14.26) is an enzyme that catalyzes the chemical reaction
The four substrates of this enzyme are 24S-hydroxycholesterol, reduced nicotinamide adenine dinucleotide phosphate (NADPH), oxygen, and a proton. Its products are (24S)-7α,24-dihydroxycholesterol, oxidised NADP+, and water.
This enzyme is a cytochrome P450-type oxidoreductase, acting on paired donors, with molecular oxygen as oxidant and incorporating one of its atoms. The systematic name of this enzyme class is (24R)-cholest-5-ene-3beta,24-diol,NADPH:oxygen oxidoreductase (7alpha-hydroxylating). Other names in common use include 24-hydroxycholesterol 7alpha-monooxygenase, CYP39A1, and CYP39A1 oxysterol 7alpha-hydroxylase.
“24-hydroxycholesterol 7alpha-hydroxylase” enters the record as class of enzymes. Crown Archives preserves that source wording while asking what 24-hydroxycholesterol, 7alpha-hydroxylase and class can confirm, complicate or overturn.
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Vocabulary and entity names are the principal evidence signals here, because they determine the precision of every later search. The source revision retrieved here is dated Mar 28, 2026. The linked authority identifier is Q3598218. None of the 0 selected statements returned an explicit reference.
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This entry incorporates text from “24-hydroxycholesterol 7alpha-hydroxylase” on English Wikipedia. Contributors are listed in the page history. Text is available under the Creative Commons Attribution-ShareAlike 4.0 License. Selected authority identifiers and statements are retrieved from Wikidata under CC0; their references and qualifiers remain part of the verification path.